The drug dichloroacetate (DCA) has so much potential for treating the metabolic dysfunction seen in cancer that the drug is undoubtedly perceived as a threat by the $126 Billion dollar cancer industry.
When a healthy cell becomes damaged, it commits suicide and kills itself in a process called apoptosis. When a healthy cell becomes cancerous, however, its ability to initiate apoptosis is shut down. Cancer grows and spreads quickly because the cell’s method of energy production switches from the oxidation of glucose, to its fermentation (in the absence of oxygen). An 80-year-old theory of German biochemist Otto Warburg was that the shift in cellular energy production that occurs within abnormal cells is the cause of cancer, and understanding how DCA works substantiates that theory.
Dr. Evangelos Michelakis and his research team from the University of Alberta discovered that DCA is very effective at re-activating the mitochondria of cancer cells, and since the mitochondria are the primary regulators of apoptosis, the cells commit suicide and eliminate themselves from the body. The mitochondria are so remarkable sensitive to DCA that they are reactivated for 48 hours after just 5 minutes of exposure.
5 Medical Studies on DCA
In 2007, Canadian researchers announced that they had been studying the drug dichloroacetate. Their results and findings from other studies since that time are as following:
- Endometrial Cancer: DCA Induces Apoptosis in Endometrial Cancer Cells. (Study)
- Prostate Cancer: DCA produced significant cytotoxic effects and was associated with an increased rate of apoptosis. (Study)
- Breast Cancer: Apoptosis and anti-proliferative effects of breast cancer cells were observed. (Study)(Study 2)
- Colorectal Cancer: Researchers found DCA reduced colon cancer tumors by 20-40%. (Study)
- Cervical Cancer: Researchers concluded that for advanced cervical carcinoma, DCA is a quick and effective cure. (Study)
Dose & Side Effects
The LD50 of DCA Orally ingested in rats is 4480 mg/kg and 5520 mg/kg for mice. In humans, the patent by Dr. Evangelos Michelakis states that anti-tumor action is achievable with a dose of DCA as low as 10 mg/kg.
The World Health Organization has stated that “To date, there have been no reports of dichloroacetic acid-induced neoplasia in any human tissue and no reports of gonadal toxicity in humans (Stacpoole et al., 1998a)”. The WHO article continued the discussion of the safety of DCA:
[quote align=”center” color=”#999999″]“Several cases of mild peripheral neuropathy following dichloroacetic acid treatment at 50–100 mg/kg of body weight per day for several months to a year have been reported. All were completely reversible after cessation of treatment. In one of these cases, dichloroacetic acid was reinstituted at 25 mg/kg of body weight per day following reversal of neurological symptoms, and this dose was maintained for 2 years without further evidence of neuropathy.”[/quote]
In a study where patients took 25mg/kg per day for three months, increased fatigue, shortness of breath, episodes of vomiting and/or gastrointestinal distress, and tremors, were reported by participants.
A survey conducted by theDCAsite highlights the following side effects reported by DCA users:
- peripheral neuropathy (tingling in the fingers)
- numbness in toes or fingers
- shaking or tremors in hands
- weakness in legs
- mild nausea
- swollen ankles
- more urination
- breathing heavier than usual_
Sodium Dichloroacetate vs Dichloroacetic Acid
In the FAQ section of theDCAsite, the following question was asked and answered:[quote align=”center” color=”#999999″]Question: I cannot find sodium dichloroacetate. Can I use dichloroacetic acid instead?
Answer: No. Never use dichloroacetic acid. Dichloroacetic acid is a terribly reactive acid. If you get it on your skin, your skin will start burning within minutes. Do not even think of drinking it. Diluting it will not help. Do not buy it. Even though dichloroacetic acid is prominently displayed on the Canada TV news clip, they did not use the acid! They used it as a precursor to make the dichloroacetate. This is not do-able by any average person. Plus, you have no way to calculate the dosage. And if you mess up on the dosage, you can really harm yourself. Do not buy the acid. Besides, you can get sodium dichloroacetate online, cheap.[/quote]
Why is DCA not being used in mainstream medicine as an alternative to chemotherapy, radiation and surgery for cancer? For one thing, DCA is extremely cheap, and for another, because no pharmaceutical company in existence has a patent on the DCA compound, they cannot claim it as their own and profit from it.
Once again the drug industry giants have suppressed from mainstream healthcare the use of a hopeful cancer cure. With the internet, we have not only all the information we need to inform ourselves about this novel compound, and we can also purchase DCA online very inexpensively.